Linked Life Data

877559

Source:http://linkedlifedata.com/resource/pubmed/id/877559

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4301
pubmed:dateCreated
1977-8-25
pubmed:abstractText
Immune complexes (bovine serum albumin with rat antibodies to bovine serum albumin) formed in twofold antibody excess were injected into the duodenum of normal rats. In comparison to controls injected with antigen only, there was a marked increase in the percentage of disrupted goblet cells (an index of mucus release) in segments from the intestine of rats exposed for 3 hours to immune complexes in vivo. Similarly, there was a significant increase in 35S-labeled mucus recovered by filtration of intestinal wash, rinse, and mucosal homogenate fluids from rats exposed to immune complexes compared to those from rats exposed to bovine serum albumin or purified rat antiserum to bovine serum albumin alone. These findings suggest that certain immune complexes can stimulate mucus release from intact rat small intestine; enhanced mucus release may have a role in clearing the surface of complexes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
197
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
370-2
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Stimulation by immune complexes of mucus release from goblet cells of the rat small intestine.
pubmed:publicationType
Journal Article