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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9027
|
pubmed:dateCreated |
1996-10-10
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pubmed:abstractText |
Discrepant analysis is a widely used technique that attempts to provide estimates of sensitivity and specificity in the presence of an imperfect gold-standard. This technique has been applied by many researchers to estimate the sensitivity and specificity of DNA-amplification tests for Chlamydia trachomatis such as the plasmid-based ligase chain-reaction and polymerase chain-reaction tests. However, the sensitivity and specificity estimates obtained by discrepant analysis are upwardly biased, and this bias remains even when a perfect test is used to resolve the discrepant results. This technique should not be adopted for evaluating the performance of a diagnostic test.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
31
|
pubmed:volume |
348
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
592-3
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:8774575-Cervix Uteri,
pubmed-meshheading:8774575-Chlamydia Infections,
pubmed-meshheading:8774575-Chlamydia trachomatis,
pubmed-meshheading:8774575-Female,
pubmed-meshheading:8774575-Gene Amplification,
pubmed-meshheading:8774575-Humans,
pubmed-meshheading:8774575-Reference Standards,
pubmed-meshheading:8774575-Sensitivity and Specificity
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pubmed:year |
1996
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pubmed:articleTitle |
The discrepancy in discrepant analysis.
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pubmed:affiliation |
Centers for Disease Control and Prevention, Center for HIV, STD, and TB prevention, Atlanta, GA 30333, USA.
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pubmed:publicationType |
Journal Article,
Review
|