|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1997-1-8
|
|
pubmed:abstractText |
Deficiency of the purine salvage pathway enzyme purine nucleoside phosphorylase causes a combined immunodeficiency and neurologic abnormalities and is usually fatal in childhood. We report the first successful transplantation of bone marrow from a sibling with identical class II human leukocyte antigens in this condition, demonstrating correction of both lymphocyte metabolic and functional abnormalities.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0022-3476
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
128
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
373-6
|
|
pubmed:dateRevised |
2004-11-17
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|
pubmed:meshHeading |
pubmed-meshheading:8774508-Bone Marrow Transplantation,
pubmed-meshheading:8774508-Child,
pubmed-meshheading:8774508-Follow-Up Studies,
pubmed-meshheading:8774508-Histocompatibility Testing,
pubmed-meshheading:8774508-Humans,
pubmed-meshheading:8774508-Immunologic Deficiency Syndromes,
pubmed-meshheading:8774508-Purine-Nucleoside Phosphorylase,
pubmed-meshheading:8774508-Purine-Pyrimidine Metabolism, Inborn Errors,
pubmed-meshheading:8774508-Time Factors,
pubmed-meshheading:8774508-Transplantation, Homologous
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
Correction of purine nucleoside phosphorylase deficiency by transplantation of allogeneic bone marrow from a sibling.
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|
pubmed:affiliation |
Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA.
|
|
pubmed:publicationType |
Journal Article,
Case Reports
|
