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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1996-10-16
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pubmed:abstractText |
We studied 10 medically intractable temporal lobe epilepsy (TLE) patients prior to surgery using proton magnetic resonance spectroscopic imaging (MRSI) to localize seizure foci. We found significantly elevated creatine/N-acetylaspartate (Cr/NAA) unilaterally in 8 and bilaterally in 2 patients. Five patients have been studied again 1 year after surgery. In the 2 patients with bilateral temporal seizure onsets, MRSI showed normalization of Cr/NAA in the unoperated contralateral tissue following surgical elimination of seizures. This study suggests that metabolic recovery can occur in contralateral temporal areas following surgical treatment of partial epilepsy.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0364-5134
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
236-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8773605-Adult,
pubmed-meshheading:8773605-Aspartic Acid,
pubmed-meshheading:8773605-Brain,
pubmed-meshheading:8773605-Cerebellum,
pubmed-meshheading:8773605-Creatinine,
pubmed-meshheading:8773605-Epilepsy, Temporal Lobe,
pubmed-meshheading:8773605-Female,
pubmed-meshheading:8773605-Functional Laterality,
pubmed-meshheading:8773605-Hippocampus,
pubmed-meshheading:8773605-Humans,
pubmed-meshheading:8773605-Magnetic Resonance Imaging,
pubmed-meshheading:8773605-Male,
pubmed-meshheading:8773605-Phosphocreatine,
pubmed-meshheading:8773605-Temporal Lobe
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pubmed:year |
1996
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pubmed:articleTitle |
Normalization of contralateral metabolic function following temporal lobectomy demonstrated by 1H magnetic resonance spectroscopic imaging.
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pubmed:affiliation |
UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham 35294-0021, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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