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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1996-10-10
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pubmed:abstractText |
Elevated plasma neurohormonal levels are associated with increased mortality rates in patients with symptomatic heart failure. A previous Studies of Left Ventricular Dysfunction (SOLVD) trial suggested that neurohumoral activation precedes the development of symptoms as demonstrated by increased neurohormonal levels in patients with asymptomatic left ventricular dysfunction. However, the significance of this early neurohumoral activation is unclear. The goals of this study were to determine the prognostic significance of the plasma concentrations of plasma norepinephrine (PNE) and atrial natriuretic peptide (ANP) and the renin activity (PRA) in patients with asymptomatic left ventricular dysfunction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0009-7322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
690-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8772689-Angina, Unstable,
pubmed-meshheading:8772689-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:8772689-Biological Markers,
pubmed-meshheading:8772689-Enalapril,
pubmed-meshheading:8772689-Female,
pubmed-meshheading:8772689-Heart Failure,
pubmed-meshheading:8772689-Humans,
pubmed-meshheading:8772689-Male,
pubmed-meshheading:8772689-Middle Aged,
pubmed-meshheading:8772689-Myocardial Infarction,
pubmed-meshheading:8772689-Myocardial Ischemia,
pubmed-meshheading:8772689-Norepinephrine,
pubmed-meshheading:8772689-Placebos,
pubmed-meshheading:8772689-Predictive Value of Tests,
pubmed-meshheading:8772689-Prognosis,
pubmed-meshheading:8772689-Renin,
pubmed-meshheading:8772689-Risk Factors,
pubmed-meshheading:8772689-Survival Rate,
pubmed-meshheading:8772689-Ventricular Dysfunction, Left
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pubmed:year |
1996
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pubmed:articleTitle |
Prognostic significance of plasma norepinephrine in patients with asymptomatic left ventricular dysfunction. SOLVD Investigators.
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pubmed:affiliation |
Division of Cardiology, University of Texas Medical School, Houston 77030, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Multicenter Study
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