|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
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|
pubmed:dateCreated |
1996-10-15
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|
pubmed:abstractText |
The multi-cytokine inducer OK-432 is a pulverized preparation of the low-virulence SU strain of Streptococcus pyogenes of human origin. A reduction of the tumour mass in the OK-432-injected areas was observed in 11 out of 13 patients with metastatic and/or recurrent head and neck cancer. Complete response (CR), partial response (PR) and minor response (MR) were noted in six, three and two cases respectively. OK-432 local administration therapy could create a new strategy for cancer therapy.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0022-2151
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
110
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
449-53
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8762314-Adult,
pubmed-meshheading:8762314-Aged,
pubmed-meshheading:8762314-Antineoplastic Agents,
pubmed-meshheading:8762314-Carcinoma, Squamous Cell,
pubmed-meshheading:8762314-Female,
pubmed-meshheading:8762314-Head and Neck Neoplasms,
pubmed-meshheading:8762314-Humans,
pubmed-meshheading:8762314-Immunologic Factors,
pubmed-meshheading:8762314-Injections, Intralesional,
pubmed-meshheading:8762314-Male,
pubmed-meshheading:8762314-Middle Aged,
pubmed-meshheading:8762314-Neoplasm Recurrence, Local,
pubmed-meshheading:8762314-Picibanil,
pubmed-meshheading:8762314-Treatment Outcome
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|
pubmed:year |
1996
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|
pubmed:articleTitle |
Inhibition of head and neck metastatic and/or recurrent cancer by local administration of multi-cytokine inducer OK-432.
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|
pubmed:affiliation |
Department of Otolaryngology, National Defense Medical College, Saitama, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
|
