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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1996-9-16
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pubmed:abstractText |
The crystallographic structure of the CAP-DNA complex at 3.0 A resolution has been reported previously. For technical reasons, the reported structure had been determined using a gapped DNA molecule lacking two phosphates important for CAP-DNA interaction. In this work, we report the crystallographic structure of the CAP-DNA complex at 2.5 A resolution using a DNA molecule having all phosphates important for CAP-DNA interaction. The present resolution permits unambiguous identification of amino acid-base and amino acid-phosphate hydrogen bonded contacts in the CAP-DNA complex. In addition, the present resolution permits accurate definition of the kinked DNA conformation in the CAP-DNA complex.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-2836
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
260
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
395-408
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pubmed:dateRevised |
2011-11-7
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pubmed:meshHeading |
pubmed-meshheading:8757802-Base Composition,
pubmed-meshheading:8757802-Base Sequence,
pubmed-meshheading:8757802-Crystallography, X-Ray,
pubmed-meshheading:8757802-Cyclic AMP Receptor Protein,
pubmed-meshheading:8757802-DNA,
pubmed-meshheading:8757802-Models, Molecular,
pubmed-meshheading:8757802-Molecular Sequence Data,
pubmed-meshheading:8757802-Nucleic Acid Conformation,
pubmed-meshheading:8757802-Phosphates,
pubmed-meshheading:8757802-Protein Conformation
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pubmed:year |
1996
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pubmed:articleTitle |
Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface.
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pubmed:affiliation |
Department of Chemistry and The Waksman Institute, Rutgers University, New Brunswick, NJ 08855-0939, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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