Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-10-9
pubmed:abstractText
Despite the alluring pharmacological properties of prostacyclin and its stable analogue (iloprost), these substances are little used in plastic surgery. A case is presented in which iloprost resulted in persistent patency of the vessels supplying a free flap. A patient who had had failure of a free flap because of thrombosis distal to the arterial anastomosis had a second free flap. Thrombus formed distal to the arterial anastomosis of the second flap and recurred when the anastomosis was redone. The flap was perfused with urokinase and then iloprost. After this, iloprost was given intravenously peroperatively and for 12 hours postoperatively. Postoperatively, the patient also received aspirin, ticlopidine and heparin. The flap survived without any late complications. A literature review offers confirmation of the advantages of using iloprost if microvascular anastomoses thrombose and during the reperfusion of flaps after prolonged ischaemia.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0007-1226
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
245-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Iloprost and salvage of a free flap.
pubmed:affiliation
Department of Plastic and Reconstructive Surgery, Hôpital de la Timone, Marseille, France.
pubmed:publicationType
Journal Article, Case Reports