|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
24
|
|
pubmed:dateCreated |
1996-11-15
|
|
pubmed:abstractText |
The aim of the review is to evaluate the putative clinical interactions between alcohol metabolism and the administration of H2-receptor antagonists. Places of the first-pass metabolism of ethanol in the body have been investigated as well. According to the in vitro experimental results the H2-receptor antagonists can inhibit the ethanol metabolism which may have clinical relevance. When low doses of alcohol (below 0.3 g/kg) are given per os, the administration of H2-receptor antagonists results in an increase in the blood ethanol concentrations. Since that challenged increase never exceeds the level of 0.3/1000 blood alcohol concentration, it has hardly any clinical or medico-legal significance.
|
|
pubmed:language |
hun
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0030-6002
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
16
|
|
pubmed:volume |
137
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1309-13
|
|
pubmed:dateRevised |
2009-10-21
|
|
pubmed:meshHeading |
pubmed-meshheading:8757090-Cimetidine,
pubmed-meshheading:8757090-Clinical Medicine,
pubmed-meshheading:8757090-Drug Interactions,
pubmed-meshheading:8757090-Ethanol,
pubmed-meshheading:8757090-Famotidine,
pubmed-meshheading:8757090-Histamine H2 Antagonists,
pubmed-meshheading:8757090-Humans,
pubmed-meshheading:8757090-Liver,
pubmed-meshheading:8757090-Nizatidine,
pubmed-meshheading:8757090-Piperidines,
pubmed-meshheading:8757090-Ranitidine,
pubmed-meshheading:8757090-Stomach
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
[H2-receptor antagonists and alcohol: clinical significance].
|
|
pubmed:affiliation |
Gasztroenterológiai és Belgyógyászati Osztály, Országos Reumatológiai és Fizioterápiás Intézet, Budapest.
|
|
pubmed:publicationType |
Journal Article,
English Abstract,
Review
|
