Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1977-8-25
pubmed:abstractText
Antipyrine and benzocaine were determined quantitatively in ear drops by high-pressure liquid chromatography on an octadecyltrichlorosilane permanently bonded to a Si-C column, using 0.02 M KH2PO4 in methanol-water as the mobile phase. Both compounds can be assayed in combination directly without interference from each other or from oxyquinoline sulfate (the preservative). The method is accurate, precise (estimated universe standard deviations of 0.68% for antipyrine and 1.18% for benzocaine), simple, and short (requires 30 min versus 2-3 hr by the NF method). The method was tried on a commercial product with excellent results and can be used in the presence of decomposition products.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0022-3549
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
897-8
pubmed:dateRevised
2000-12-18
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Quantitative determinations of antipyrine and benzocaine in ear drops by high-pressure liquid chromatography.
pubmed:publicationType
Journal Article