Linked Life Data

8745925

Source:http://linkedlifedata.com/resource/pubmed/id/8745925

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1996-10-30
pubmed:abstractText
The public-health problems caused by leishmaniasis in most countries in Central America are becoming more severe. This is partly because of the increasing size of the human populations that are at risk and their migratory patterns. Annual incidence of the disease in Costa Rica, Honduras, Guatemala, Panama and Nicaragua is estimated to be as high as 20,000 cases. Regional changes in the epidemiology of the various Leishmania spp. present have emphasized the need for innovative, sensitive and accurate diagnostic tools. PCR and isoenzyme, monoclonal antibody, schizodeme, DNA-probe and random-amplified, polymorphic DNA analyses have been tested. Preliminary indications that Leishmania chagasi was present in Costa Rica and Honduras and that interspecific hybrids occurred in Nicaragua have been confirmed using these methods. The distribution of the mexicana complex was also found to be broader and more heterogeneous than initially expected. Overall, there was 87% concordance between the results produced using the different techniques.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0003-4983
pubmed:author
pubmed:issnType
Print
pubmed:volume
89 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-36
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Molecular techniques in the characterization of Leishmania isolates from Central America.
pubmed:affiliation
Centro de Investigación y Diagnóstico de Enfermedades Parasitarias, Universidad de Panamá.
pubmed:publicationType
Journal Article, Comparative Study