|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1996-11-5
|
|
pubmed:abstractText |
8-Chloroadenosine 3',5'-monophosphate (8-Cl-cAMP) is undergoing phase I clinical trials as an anticancer drug. However, there is debate as to whether it is a prodrug for its 8-Cl-adenosine metabolite.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0923-7534
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
7
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
291-6
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:8740794-8-Bromo Cyclic Adenosine Monophosphate,
pubmed-meshheading:8740794-Animals,
pubmed-meshheading:8740794-Antineoplastic Agents,
pubmed-meshheading:8740794-Breast Neoplasms,
pubmed-meshheading:8740794-Colonic Neoplasms,
pubmed-meshheading:8740794-Humans,
pubmed-meshheading:8740794-Infusions, Intravenous,
pubmed-meshheading:8740794-Mice,
pubmed-meshheading:8740794-Mice, Nude,
pubmed-meshheading:8740794-Prodrugs,
pubmed-meshheading:8740794-Tissue Distribution,
pubmed-meshheading:8740794-Transplantation, Heterologous
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
Pharmacokinetics, metabolism and tumour disposition of 8-chloroadenosine 3',5'-monophosphate in breast cancer patients and xenograft bearing mice.
|
|
pubmed:affiliation |
Imperial Cancer Research Fund, Western General Hospital, Edinburgh, U.K.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Clinical Trial, Phase I
|
