Linked Life Data

8740096

Source:http://linkedlifedata.com/resource/pubmed/id/8740096

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-10-16
pubmed:abstractText
In children with cancer a reduced neutral urine DNase activity was observed at the end of cytostatic therapy. It is presumed that disorders in the kidney functions are the cause. A low neutral DNase activity is found in the blood; the activity is inhibited by inhibitors. The inhibitors of the enzyme are split away in the kidneys so that the neutral DNase activity in urine increases. Many cytostatic drugs can induce damage to the kidneys. This may be the reason that not all inhibitors of neutral DNase are split away in the kidneys and the activity of the neutral urine DNase is reduced at the end of cytostatic therapy. The process of removing the inhibitors is independent of the filtering capacity of the kidneys.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0004-4172
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
438-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Reduced neutral DNase activity in the urine of children after cytostatic therapy.
pubmed:affiliation
Clinics of Anesthesiology, University of Mainz, Germany.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't