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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1996-10-16
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pubmed:abstractText |
The effects of Thiotepa, Mitomycin C, BCG and Interferon on urothelium were researched in rabbits. Early changes of a contracted bladder such as fibroblastic atypia and sub-epithelial plaque were seen in all groups in different rates. This rate in the Thiotepa and BCG groups was 100% and in the Mitomycin C and Interferon groups 60%. There was no urothelial dysplasia in the BCG and Interferon groups, whereas in the Thiotepa group 100% and in the Mitomycin C group 40% were seen. In conclusion, urothelial dysplasia or fibroblastic atypia in random biopsies were criteria to prevent further complications in intravesical therapies.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0301-1623
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8738618-Administration, Intravesical,
pubmed-meshheading:8738618-Animals,
pubmed-meshheading:8738618-Antineoplastic Agents,
pubmed-meshheading:8738618-BCG Vaccine,
pubmed-meshheading:8738618-Epithelium,
pubmed-meshheading:8738618-Interferons,
pubmed-meshheading:8738618-Mitomycin,
pubmed-meshheading:8738618-Rabbits,
pubmed-meshheading:8738618-Thiotepa,
pubmed-meshheading:8738618-Urinary Bladder
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pubmed:year |
1996
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pubmed:articleTitle |
The effects of thiotepa, mitomycin C, BCG and interferon instillation on urothelium.
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pubmed:affiliation |
Department of Urology, Atatürk University School of Medicine, Research Hospital, Erzurum, Turkey.
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pubmed:publicationType |
Journal Article
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