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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1979-8-29
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pubmed:abstractText |
The reaginic antibody response to alum-precipitated ovalbumin (OA) and the dialyzed water-soluble extracts of ragweed (DWSR) and Alternaria tenuis (DWST) in several strains of rats appeared to be wholly an IgE response. There was no evidence of a heat-stable (IgGa) antibody to OA, DWSR and DWST in the sera of the rats immunized with these antigens suspended in alum. Wistar-Furth and Lew inbred and hooded outbred rats produced comparable amounts of reaginic antibody after immunization with DWST, but BN inbred rats failed to generate a reaginic response to this antigen. The amount of antigen-induced histamine release from rat peritoneal mast cells did not always correlate with the level of circulating IgE-specific antibody.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0020-5915
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
227-32
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:87378-Adsorption,
pubmed-meshheading:87378-Alternaria,
pubmed-meshheading:87378-Alum Compounds,
pubmed-meshheading:87378-Aluminum,
pubmed-meshheading:87378-Animals,
pubmed-meshheading:87378-Antibody Formation,
pubmed-meshheading:87378-Antigens,
pubmed-meshheading:87378-Female,
pubmed-meshheading:87378-Histamine Release,
pubmed-meshheading:87378-Immune Sera,
pubmed-meshheading:87378-Immunoglobulin E,
pubmed-meshheading:87378-Male,
pubmed-meshheading:87378-Passive Cutaneous Anaphylaxis,
pubmed-meshheading:87378-Plant Extracts,
pubmed-meshheading:87378-Rats,
pubmed-meshheading:87378-Rats, Inbred BN,
pubmed-meshheading:87378-Rats, Inbred Lew,
pubmed-meshheading:87378-Rats, Inbred WF,
pubmed-meshheading:87378-Reagins
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pubmed:year |
1979
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pubmed:articleTitle |
Preferential synthesis of IgE reaginic antibodies in rats immunized with alum-adsorbed antigens.
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pubmed:publicationType |
Journal Article
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