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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1996-11-12
|
pubmed:abstractText |
The mode of replication of the hepatitis C virus (HCV) remains poorly understood. Attempts to produce a tissue culture model containing replicating HCV have been largely unsuccessful. Recent studies on sera from patients chronically infected with HCV have shown that viral particles may be found in high- or low-density fractions. High-density fractions contain non-infectious virions whilst infectious particles can be derived from low-density material. Using appropriate infectious fractions we have successfully infected a number of human cell lines allowing studies of HCV replication to be initiated.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1352-0504
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3-10
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8736234-Animals,
pubmed-meshheading:8736234-B-Lymphocytes,
pubmed-meshheading:8736234-Cell Line,
pubmed-meshheading:8736234-Cell Line, Transformed,
pubmed-meshheading:8736234-Hepacivirus,
pubmed-meshheading:8736234-Hepatitis C,
pubmed-meshheading:8736234-Host-Parasite Interactions,
pubmed-meshheading:8736234-Humans,
pubmed-meshheading:8736234-Liver,
pubmed-meshheading:8736234-Pan troglodytes,
pubmed-meshheading:8736234-T-Lymphocytes,
pubmed-meshheading:8736234-Virus Replication
|
pubmed:year |
1996
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pubmed:articleTitle |
Replication of hepatitis C virus.
|
pubmed:affiliation |
Department of Bacteriology, Faculty of Medicine, University of Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|