Linked Life Data

8736167

Source:http://linkedlifedata.com/resource/pubmed/id/8736167

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-10-15
pubmed:abstractText
The objective of this study was to determine whether elevated levels of N-ras correlated with clinicopathological data. Complete clinical data were available on 133 of 481 patients surgically treated for squamous cell carcinoma of the head and neck (SCCHN) who had immunohistochemical data for N-ras. Advanced stages of disease were strongly related to the staining for N-ras in tumour cells (P = 0.0031). The stage of disease was inversely related to duration of survival (P = 0.0017). Initial statistical evaluation revealed an apparent correlation between survival and N-ras staining. However, duration was found to be independent of the level of N-ras. The illusory relationship initially was a result of the confounding effect of the stage of disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0964-1955
pubmed:author
pubmed:issnType
Print
pubmed:volume
32B
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
73-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Stage of disease confounds apparent relationship between levels of N-ras and duration of survival in head and neck tumours.
pubmed:affiliation
Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Ohio 45267-0528, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't