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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1996-11-14
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pubmed:abstractText |
Study of 22 patients with the severe form of neurocysticercosis treated with albendazole (ABZ) administered in 6 different schedules ranging from 15 to 30 mg/kg/day for 21 to 60 days. Dextrochloropheniramine and ketoprofen were the adjuvant drugs. Multiple symptoms were observed in 90.9% of patients. Intracranial hypertension was manifested in 90.9%. Hydrocephaly occurred in 86.4%. Evolution was satisfactory in 10 patients, 8 died and 4 had sequelae. Tomographic studies showed the appearance of an isolated IVth ventricle in 9 patients, after ventriculoperitoneal shunt, before ABZ treatment in 3 of them, during in 5 and after treatment in one. Median clinical follow-up duration was 10 months for the patients who died and 3-4 years for survivors. In 3 patients there was an increase in cyst size during the administration of the 15 mg/kg/day ABZ dose, which was not observed in any patient when the 30 mg/kg/day dose was used.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Albendazole,
http://linkedlifedata.com/resource/pubmed/chemical/Anthelmintics,
http://linkedlifedata.com/resource/pubmed/chemical/Chlorpheniramine,
http://linkedlifedata.com/resource/pubmed/chemical/Ketoprofen,
http://linkedlifedata.com/resource/pubmed/chemical/dexchlorpheniramine
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0004-282X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
82-93
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:8736150-Adolescent,
pubmed-meshheading:8736150-Adult,
pubmed-meshheading:8736150-Albendazole,
pubmed-meshheading:8736150-Anthelmintics,
pubmed-meshheading:8736150-Brain Diseases,
pubmed-meshheading:8736150-Chlorpheniramine,
pubmed-meshheading:8736150-Cysticercosis,
pubmed-meshheading:8736150-Female,
pubmed-meshheading:8736150-Follow-Up Studies,
pubmed-meshheading:8736150-Humans,
pubmed-meshheading:8736150-Ketoprofen,
pubmed-meshheading:8736150-Male,
pubmed-meshheading:8736150-Middle Aged,
pubmed-meshheading:8736150-Prognosis,
pubmed-meshheading:8736150-Tomography, X-Ray Computed
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pubmed:year |
1996
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pubmed:articleTitle |
Severe forms of neurocysticercosis: treatment with albendazole.
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pubmed:affiliation |
Department of Neurology and Psychiatry, State University of São Paulo, UNESP, Brasil.
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pubmed:publicationType |
Journal Article
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