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pubmed:abstractText |
In this study, we investigated whether nicotine may have a local anaesthetic action in mice, using the tail press and tail immersion tests. Nicotine increased the latent time of biting the clip in the tail press test (p < 0.001) and retarded tail withdrawal latency in the tail immersion test (p < 0.01), compared to controls. These results suggest that nicotine may possess a local anaesthetic action.
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