pubmed-article:8735556 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8735556 | lifeskim:mentions | umls-concept:C0020971 | lld:lifeskim |
pubmed-article:8735556 | lifeskim:mentions | umls-concept:C0036125 | lld:lifeskim |
pubmed-article:8735556 | lifeskim:mentions | umls-concept:C0042210 | lld:lifeskim |
pubmed-article:8735556 | lifeskim:mentions | umls-concept:C1545588 | lld:lifeskim |
pubmed-article:8735556 | lifeskim:mentions | umls-concept:C0439234 | lld:lifeskim |
pubmed-article:8735556 | lifeskim:mentions | umls-concept:C0205473 | lld:lifeskim |
pubmed-article:8735556 | lifeskim:mentions | umls-concept:C0148358 | lld:lifeskim |
pubmed-article:8735556 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:8735556 | pubmed:dateCreated | 1996-10-17 | lld:pubmed |
pubmed-article:8735556 | pubmed:abstractText | The protective efficacy and immunogenicity of Vi capsular polysaccharide vaccine against typhoid fever was measured 3 years after its administration in a double-blind randomized trial. Vaccine efficacy was not significantly different during each year of the trial and was 55% (95% CI: 30-71%) over the 3 year period. In a case-control study at 3 years after vaccination, recipients of Vi had higher levels of Vi antibodies than controls, as measured by radio-immunoassay (GMT 1.28 vs 0.76 microgram ml-1, P = 0.0004) and by passive haemagglutination assay (GMT 10.46 vs 3.52, P = 0.0001). The serological correlate of protection has been estimated using the relative risks of typhoid fever in the 2 groups and the relative ratio of antibody levels. The estimated protective level is 1 microgram ml-1 suggesting that at a mean age of 9 years, 64% of vaccinates and 40% of controls had protective antibody against typhoid fever in this endemic area. | lld:pubmed |
pubmed-article:8735556 | pubmed:language | eng | lld:pubmed |
pubmed-article:8735556 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8735556 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8735556 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8735556 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8735556 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8735556 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8735556 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8735556 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8735556 | pubmed:month | Apr | lld:pubmed |
pubmed-article:8735556 | pubmed:issn | 0264-410X | lld:pubmed |
pubmed-article:8735556 | pubmed:author | pubmed-author:KoornhofH JHJ | lld:pubmed |
pubmed-article:8735556 | pubmed:author | pubmed-author:RobbinsJ BJB | lld:pubmed |
pubmed-article:8735556 | pubmed:author | pubmed-author:KlugmanK PKP | lld:pubmed |
pubmed-article:8735556 | pubmed:author | pubmed-author:Le CamN NNN | lld:pubmed |
pubmed-article:8735556 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8735556 | pubmed:volume | 14 | lld:pubmed |
pubmed-article:8735556 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8735556 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8735556 | pubmed:pagination | 435-8 | lld:pubmed |
pubmed-article:8735556 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:8735556 | pubmed:year | 1996 | lld:pubmed |
pubmed-article:8735556 | pubmed:articleTitle | Immunogenicity, efficacy and serological correlate of protection of Salmonella typhi Vi capsular polysaccharide vaccine three years after immunization. | lld:pubmed |
pubmed-article:8735556 | pubmed:affiliation | Department of Medical Microbiology, School of Pathology, SAIMR/University of the Witwatersrand, Johannesburg, South Africa. | lld:pubmed |
pubmed-article:8735556 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8735556 | pubmed:publicationType | Clinical Trial | lld:pubmed |
pubmed-article:8735556 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
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