Linked Life Data

8735191

Source:http://linkedlifedata.com/resource/pubmed/id/8735191

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1996-10-25
pubmed:abstractText
The present studies were designed to determine the role of reactive vascular smooth muscle in the regulation of blood flow into and out of the cavernous sinuses during penile erection in castrated and testosterone-treated animals. While the mean arterial pressure and intracavernosal pressure were continuously monitored, vasoactive drugs were injected into the aorta or into the cavernous sinuses during erection. The results show that both a NO releasing vasodilatory drug and an alpha adrenergic agonist significantly affected both mean arterial pressure and intracavernosal pressure when injected into the aorta. However, when these same drugs were injected into the cavernous sinuses, neither drug exerted a significant influence on the erectile response. Based on these studies, we conclude that the flow of blood into the cavernous sinuses during erection is regulated by reactive vascular smooth muscle but the outflow is not under the regulation of reactive vascular smooth muscle. Furthermore, the relaxation of the smooth muscle which controls the flow of blood into the cavernous sinuses during erection may be under partial androgenic control.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0955-9930
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-34
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Sites of androgenic regulation of cavernosal blood pressure during penile erection in the rat.
pubmed:affiliation
Department of Physiology and Endocrinology, Medical College of Georgia, Augusta 30912-3000, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't