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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
|
pubmed:dateCreated |
1996-10-16
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pubmed:abstractText |
Patients with seasonal affective disorder (SAD) were treated for 1 week either with a daily 1-h morning walk outdoors (natural light) or low-dose artificial light (0.5 h@2800 lux). The latter treatment (given under double-blind conditions) can be considered mainly placebo and did not improve any of the depression self-ratings, whereas natural light exposure improved all self-ratings. According to the Hamilton depression score, 25% remitted after low-dose artificial light and 50% after the walk. Sleep duration or timing were not crucial for the therapeutic response. The morning walk phase-advanced the onset and/or offset of salivary melatonin secretion, but individual clinical improvement could not be correlated with specific phase-shifts. Morning cortisol was decreased. Low-dose artificial light did not modify melatonin or cortisol patterns. This is the first study to provide evidence for the use of outdoor light exposure as a potential alternative or adjuvant to conventional artificial light therapy in SAD.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0165-0327
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
37
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
109-20
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pubmed:dateRevised |
2009-9-28
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pubmed:meshHeading |
pubmed-meshheading:8731073-Adult,
pubmed-meshheading:8731073-Circadian Rhythm,
pubmed-meshheading:8731073-Double-Blind Method,
pubmed-meshheading:8731073-Female,
pubmed-meshheading:8731073-Humans,
pubmed-meshheading:8731073-Hydrocortisone,
pubmed-meshheading:8731073-Male,
pubmed-meshheading:8731073-Melatonin,
pubmed-meshheading:8731073-Middle Aged,
pubmed-meshheading:8731073-Personality Inventory,
pubmed-meshheading:8731073-Phototherapy,
pubmed-meshheading:8731073-Saliva,
pubmed-meshheading:8731073-Seasonal Affective Disorder,
pubmed-meshheading:8731073-Sleep Stages,
pubmed-meshheading:8731073-Sunlight,
pubmed-meshheading:8731073-Treatment Outcome,
pubmed-meshheading:8731073-Walking
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pubmed:year |
1996
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pubmed:articleTitle |
'Natural' light treatment of seasonal affective disorder.
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pubmed:affiliation |
Psychiatric University Clinic, Basel, Switzerland.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, Non-P.H.S.,
Randomized Controlled Trial
|