Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1996-10-24
pubmed:abstractText
Bartonella quintana is a reemerging pathogen responsible for trench fever, endocarditis, bacteremia, and bacillary angiomatosis. We previously reported the first case of a patient with B. quintana-induced chronic adenomegaly, and here we present a report on a second patient. A hemodialyzed patient with Sjögren's syndrome presented with mediastinal adenomegalies and secondary pancytopenia. All diagnostic investigations remained negative, except that a Bartonella-like microorganism was isolated from a bone marrow biopsy. The isolate was identified as B. quintana by a specific mouse polyclonal antibody and by determination of a partial gltA (citrate synthase-encoding) gene and 16S rRNA gene sequences. DNA of the pathogen was also detected in the adenomegaly and in the serum of the patient by PCR amplification of the gltA gene. Anti-B. quintana antibodies were never detected in the patient's serum throughout the 12-month follow-up but were detected in the serum of the patient's cat. The patient's outcome was favorable after treatment with gentamicin. Chronic adenomegaly in seronegative patients is a new clinical entity due to B. quintana.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-1371515, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-1408846, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-1435899, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-5297000, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-7519628, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-7527255, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-7529894, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-7529895, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-7545183, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-7853966, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-7909030, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-8301768, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-8537257, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-8562744, http://linkedlifedata.com/resource/pubmed/commentcorrection/8727894-8585713
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1158-60
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Bartonella (Rochalimaea) quintana infection in a seronegative hemodialyzed patient.
pubmed:affiliation
Unité des Rickettsies, Faculté de Médecine, Centre National de la Recherche Scientifique, Marseille, France.
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't