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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1996-11-22
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pubmed:abstractText |
Standardized heart rate analyses were performed in 60 drug-free patients with alcohol dependence, who were admitted consecutively to a psychiatric department, and in 60 healthy normal matched subjects. The procedure included time and frequency derived measurements of heart rate variability (HRV). The investigations were carried out 3 weeks after admission and treatment on a closed ward to avoid autonomic hyperexcitability during withdrawal or relapse. The patients showed a significantly increased heart rate (p < 0.05), a significant reduction in the coefficient of variation while resting (p < 0.01) and a significant decrease of the high frequency power of spectral analysis (p < 0.01) compared with the normal subjects. Cardiovascular autonomic dysfunction was found in 12 of the patients, but in only one of the normal subjects (p < 0.01). The results indicated moderate parasympathetic (vagal) alteration in alcohol-dependent patients treated in a psychiatric department. This may have implications for psychotherapeutic or psychopharmacological treatment strategies and prognosis in such patients with alcohol dependence.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0959-9851
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
119-22
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8726098-Adult,
pubmed-meshheading:8726098-Alcoholism,
pubmed-meshheading:8726098-Autonomic Nervous System Diseases,
pubmed-meshheading:8726098-Cardiovascular Diseases,
pubmed-meshheading:8726098-Female,
pubmed-meshheading:8726098-Heart Rate,
pubmed-meshheading:8726098-Humans,
pubmed-meshheading:8726098-Male,
pubmed-meshheading:8726098-Middle Aged,
pubmed-meshheading:8726098-Psychiatric Department, Hospital,
pubmed-meshheading:8726098-Substance Withdrawal Syndrome
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pubmed:year |
1996
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pubmed:articleTitle |
Autonomic cardiac abnormalities in alcohol-dependent patients admitted to a psychiatric department.
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pubmed:affiliation |
Department of Psychiatry, University of Erlangen-Nürnberg, Germany.
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pubmed:publicationType |
Journal Article
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