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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-2-5
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pubmed:databankReference |
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pubmed:abstractText |
A new mutation, bglJ4, has been characterized that results in the expression of the silent bgl operon. The bgl operon encodes proteins necessary for the transport and utilization of the aromatic beta-glucosides arbutin and salicin. A variety of mutations activate the operon and result in a Bgl+ phenotype. Activating mutations are located upstream of the bgl promoter and in genes located elsewhere on the chromosome. Mutations outside of the bgl operon occur in the genes encoding DNA gyrase and in the gene encoding the nucleoid associated protein H-NS. The mutation described here, bglJ4, has been mapped to a new locus at min 99 on the Escherichia coli K-12 genetic map. The putative protein encoded by the bglJ gene has homolgy to a family of transcriptional activators. Evidence is presented that increased expression of the bglJ product is needed for activation of the bgl operon.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-1311089,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-1360005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-1382312,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-1630307,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-1691451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-1698125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-1745240,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-1961761,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-1999391,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2128918,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2177526,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2179048,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2184240,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2194094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2200123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2231712,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2314271,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2537812,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2673534,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2841565,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-2852142,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-3025456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-3034860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-3043141,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-3294798,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-3301003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-3301805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-3552873,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-4607165,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-4616943,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-5335893,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-6266910,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-6270569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-6289329,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-6297752,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-6311437,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-6400646,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-6403503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-7534408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-7610040,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-7934818,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-8057848,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-8437561,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8725214-8458322
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0016-6731
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
143
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
627-35
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8725214-Amino Acid Sequence,
pubmed-meshheading:8725214-Base Sequence,
pubmed-meshheading:8725214-Chromosome Mapping,
pubmed-meshheading:8725214-Escherichia coli,
pubmed-meshheading:8725214-Escherichia coli Proteins,
pubmed-meshheading:8725214-Genes, Bacterial,
pubmed-meshheading:8725214-Molecular Sequence Data,
pubmed-meshheading:8725214-Mutation,
pubmed-meshheading:8725214-Operon,
pubmed-meshheading:8725214-Trans-Activators
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pubmed:year |
1996
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pubmed:articleTitle |
A mutation in a new gene, bglJ, activates the bgl operon in Escherichia coli K-12.
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pubmed:affiliation |
Biology Department, Simmons College, Boston, Massachusetts 02115, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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