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| pubmed-article:8723477 | lifeskim:mentions | umls-concept:C0525278 | lld:lifeskim |
| pubmed-article:8723477 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8723477 | pubmed:dateCreated | 1996-10-25 | lld:pubmed |
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| pubmed-article:8723477 | pubmed:abstractText | We investigated the molecular mechanism of 50 penicillin-resistant Streptococcus pneumoniae strains (penicillin: MIC, > or = 0.125 microgram/ml) having neither class A nor class B mutations in the penicillin-binding protein 2B gene (pbp2b). An analysis of the nucleotide sequences of the pbp2b genes from seven strains revealed an unique direct repeat of 9 nucleotides (TGGTATACT) between active-site serine (residue 385) and Ser-X-Asn (residues 442 to 444) motifs. The same insertion was detected in 13 strains. | lld:pubmed |
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| pubmed-article:8723477 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:8723477 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8723477 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8723477 | pubmed:month | May | lld:pubmed |
| pubmed-article:8723477 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:8723477 | pubmed:author | pubmed-author:NakanoHH | lld:pubmed |
| pubmed-article:8723477 | pubmed:author | pubmed-author:KonnoMM | lld:pubmed |
| pubmed-article:8723477 | pubmed:author | pubmed-author:YamaneAA | lld:pubmed |
| pubmed-article:8723477 | pubmed:author | pubmed-author:UbukataKK | lld:pubmed |
| pubmed-article:8723477 | pubmed:author | pubmed-author:AsahiYY | lld:pubmed |
| pubmed-article:8723477 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8723477 | pubmed:volume | 40 | lld:pubmed |
| pubmed-article:8723477 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8723477 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8723477 | pubmed:pagination | 1257-9 | lld:pubmed |
| pubmed-article:8723477 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:8723477 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8723477 | pubmed:articleTitle | Directly repeated insertion of 9-nucleotide sequence detected in penicillin-binding protein 2B gene of penicillin-resistant Streptococcus pneumoniae. | lld:pubmed |
| pubmed-article:8723477 | pubmed:affiliation | Institute for Biotechnology Research, Wakunaga Pharmaceutical Co., Ltd., Hiroshima, Japan. | lld:pubmed |
| pubmed-article:8723477 | pubmed:publicationType | Journal Article | lld:pubmed |
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