Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1977-9-2
|
pubmed:abstractText |
The daily rate of cell replication in the aortic endothelium of the normal rat falls from a maximum of 13% at birth to 0.1-0.3% at age 5-6 months. This residual rate of replication largely represents the turnover rate of the endothelium in normal animals. After renal hypertension of 2-3 weeks duration, however, the rate of replication rises 10-fold to an average value of 1.6%. This increase may represent an increase in turnover; however, it probably represent, at least in part, a proliferative response to cover the expanded luminal surface of the dilated vessel.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0009-7330
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
41
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
248-55
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:872300-Age Factors,
pubmed-meshheading:872300-Animals,
pubmed-meshheading:872300-Aorta,
pubmed-meshheading:872300-Arteries,
pubmed-meshheading:872300-Blood Pressure Determination,
pubmed-meshheading:872300-Cell Division,
pubmed-meshheading:872300-Endothelium,
pubmed-meshheading:872300-Female,
pubmed-meshheading:872300-Hypertension,
pubmed-meshheading:872300-Methods,
pubmed-meshheading:872300-Rats,
pubmed-meshheading:872300-Tritium
|
pubmed:year |
1977
|
pubmed:articleTitle |
Aortic endothelial cell replication. I. Effects of age and hypertension in the rat.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|