rdf:type |
|
lifeskim:mentions |
umls-concept:C0007589,
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0206427,
umls-concept:C1145667,
umls-concept:C1171362,
umls-concept:C1511938,
umls-concept:C1515670,
umls-concept:C2355587
|
pubmed:issue |
1-2
|
pubmed:dateCreated |
1996-9-18
|
pubmed:abstractText |
It has been shown previously that the transcription factor Mash-1 plays a significant role in mammalian neurogenesis. In the present study we show that Mash-1 is expressed during rat retinal development and that it interacts specifically with an E-box identified in the promoter of the opsin gene during rod photoreceptor differentiation. We propose that opsin may be one of the downstream neuronal genes regulated by Mash-1 during neurogenesis in the central nervous system.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0165-3806
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
21
|
pubmed:volume |
90
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
184-9
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:8719343-Animals,
pubmed-meshheading:8719343-Base Sequence,
pubmed-meshheading:8719343-Basic Helix-Loop-Helix Transcription Factors,
pubmed-meshheading:8719343-DNA-Binding Proteins,
pubmed-meshheading:8719343-Evaluation Studies as Topic,
pubmed-meshheading:8719343-Gene Expression Regulation, Developmental,
pubmed-meshheading:8719343-Helix-Loop-Helix Motifs,
pubmed-meshheading:8719343-Molecular Sequence Data,
pubmed-meshheading:8719343-Promoter Regions, Genetic,
pubmed-meshheading:8719343-Rats,
pubmed-meshheading:8719343-Regulatory Sequences, Nucleic Acid,
pubmed-meshheading:8719343-Retinal Rod Photoreceptor Cells,
pubmed-meshheading:8719343-Rod Opsins,
pubmed-meshheading:8719343-Transcription Factors
|
pubmed:year |
1995
|
pubmed:articleTitle |
Mash-1 is expressed during ROD photoreceptor differentiation and binds an E-box, E(opsin)-1 in the rat opsin gene.
|
pubmed:affiliation |
Department of Cell Biology and Anatomy and Ophthalmology, University of Nebraska Medical Center, Omaha 68198, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|