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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1996-9-10
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pubmed:abstractText |
Although the short-term outcome of total parathyroidectomy combined with autotransplantation in cases of renal osteodystrophy has been reported by many investigators, few studies have been made on the long-term outcome of this surgical technique. We recently examined the long-term outcome of this surgery by following 19 cases for more than one year (range: 12-70 months, mean: 31.7 months). During the follow-up period, changes in subjective symptoms, biochemical parameters and bone mineral density (BMD) were monitored. At the end of the follow-up period, C-parathyroid hormone (C-PTH) and alkaliphosphatase (ALP) were significantly lower than their preoperative levels. Ca, P and %BMD showed no significant change from their preoperative levels, although %BMD tended to be higher than its preoperative level. Depending on the presence or absence of osteoarticular pain at the end of the follow-up period, the patients were divided into the improved group and the non-improved group. Of the 5 patients allocated to the non-improved group, 4 were female and only 1 was male. C-PTH and ALP were significantly higher in the non-improved group. %BMD was higher in the improved group than in the non-improved group, although this difference was not significant. In the non-improved group, 2 patients were suspected of having extra parathyroids, 1 was suspected of having recurrence, and 2 were suspected of having postoperative osteomalacia. Postoperative reduction in BMD was only seen in females, suggesting its relationship to postmenopausal osteoporosis.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0018-1994
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
105-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8712083-Adult,
pubmed-meshheading:8712083-Alkaline Phosphatase,
pubmed-meshheading:8712083-Bone Density,
pubmed-meshheading:8712083-Female,
pubmed-meshheading:8712083-Follow-Up Studies,
pubmed-meshheading:8712083-Humans,
pubmed-meshheading:8712083-Hyperparathyroidism, Secondary,
pubmed-meshheading:8712083-Male,
pubmed-meshheading:8712083-Middle Aged,
pubmed-meshheading:8712083-Parathyroid Glands,
pubmed-meshheading:8712083-Parathyroid Hormone,
pubmed-meshheading:8712083-Parathyroidectomy,
pubmed-meshheading:8712083-Time Factors,
pubmed-meshheading:8712083-Transplantation, Autologous,
pubmed-meshheading:8712083-Treatment Outcome
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pubmed:year |
1996
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pubmed:articleTitle |
[Long-term effect after total parathyroidectomy with autotransplantation for secondary hyperparathyroidism].
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pubmed:affiliation |
Department of Urology, Kinki University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract
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