Linked Life Data

8711912

Source:http://linkedlifedata.com/resource/pubmed/id/8711912

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1996-9-12
pubmed:abstractText
We studied frequencies and dynamic characteristics of anticipatory smooth eye movements (ASEM) in humans who were tracking step target movements of 20-70 deg amplitude. During presentation of periodic steps of constant amplitude healthy subjects showed frequent high velocity ASEM reaching maximal peak velocities of 5-40 deg/sec. There was no effect of ASEM on the frequency of anticipatory saccades. Randomization of target step amplitude or onset reduced the frequency of ASEM but did not completely abolish fast ASEM. In patients with cerebellar degeneration who exhibited impaired smooth pursuit, fast ASEM were absent and the number of slow ASEM was minimal. In conclusion, large sequential target steps can elicit much higher ASEM velocities than typically described in the literature. Similar to slow ASEM triggered by small steps, these fast ASEM do not require specific training and are not canceled by unpredictable step target motion. However, fast ASEM depend on the intact function of the cerebellum which gives further evidence of their generation by the smooth pursuit oculomotor subsystem.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0042-6989
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1341-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Anticipatory smooth eye movements of high velocity triggered by large target steps: normal performance and effect of cerebellar degeneration.
pubmed:affiliation
Department of Neurology, University of Hamburg, Germany.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't