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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1996-9-9
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pubmed:abstractText |
Two middle-aged patients with T cell lymphoma, both natives of Bucharest, Romania, tested positive for HTLV-I antibodies. Malignant cells had the typical phenotype and morphology of adult T cell leukemia/lymphoma (ATL). Both cases presented with extranodal manifestation, hypercalcemia, early recurrence after initial responses to therapy, and subsequent resistance to conventional and intensified chemotherapy. Infection with HTLV-I was confirmed by PCR analyses of serial biopsies. Neither patient reported known risk factors for HTLV-I infection. This report points to the possibility that Romania may represent an endemic area for HTLV-I and should heighten the awareness towards HTLV-I infections in Romanian patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0887-6924
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1366-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8709646-Adult,
pubmed-meshheading:8709646-Antigens, CD,
pubmed-meshheading:8709646-Base Sequence,
pubmed-meshheading:8709646-Biopsy,
pubmed-meshheading:8709646-DNA, Viral,
pubmed-meshheading:8709646-DNA Primers,
pubmed-meshheading:8709646-Female,
pubmed-meshheading:8709646-HTLV-I Antibodies,
pubmed-meshheading:8709646-Human T-lymphotropic virus 1,
pubmed-meshheading:8709646-Humans,
pubmed-meshheading:8709646-Immunohistochemistry,
pubmed-meshheading:8709646-Immunophenotyping,
pubmed-meshheading:8709646-Leukemia-Lymphoma, Adult T-Cell,
pubmed-meshheading:8709646-Male,
pubmed-meshheading:8709646-Molecular Sequence Data,
pubmed-meshheading:8709646-Polymerase Chain Reaction,
pubmed-meshheading:8709646-Romania
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pubmed:year |
1996
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pubmed:articleTitle |
HTLV-I-associated adult T cell leukemia/lymphoma in two patients from Bucharest, Romania.
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pubmed:affiliation |
Department of Internal Medicine I (Hematology/Oncology), Freiburg University Medical Center, Germany.
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pubmed:publicationType |
Journal Article,
Case Reports
|