|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0016360,
umls-concept:C0023413,
umls-concept:C0030231,
umls-concept:C0034656,
umls-concept:C0036525,
umls-concept:C0205179,
umls-concept:C0205195,
umls-concept:C0206012,
umls-concept:C0332174,
umls-concept:C1096776,
umls-concept:C1257890,
umls-concept:C1274040,
umls-concept:C1522484,
umls-concept:C1527249,
umls-concept:C2348563,
umls-concept:C2603343
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
1996-9-6
|
|
pubmed:abstractText |
To determine the most effective dose of leucovorin (folinic acid [FA]) within a weekly bolus fluorouracil (FU) schedule, we conducted a randomized multicenter trial to compare therapeutic effects and toxicity of high-dose FA versus low-dose FA combined with FU at equal doses in both treatment groups.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0732-183X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2274-9
|
|
pubmed:dateRevised |
2009-11-3
|
|
pubmed:meshHeading |
pubmed-meshheading:8708717-Adult,
pubmed-meshheading:8708717-Aged,
pubmed-meshheading:8708717-Aged, 80 and over,
pubmed-meshheading:8708717-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:8708717-Colorectal Neoplasms,
pubmed-meshheading:8708717-Diarrhea,
pubmed-meshheading:8708717-Disease-Free Survival,
pubmed-meshheading:8708717-Drug Administration Schedule,
pubmed-meshheading:8708717-Female,
pubmed-meshheading:8708717-Fluorouracil,
pubmed-meshheading:8708717-Germany,
pubmed-meshheading:8708717-Humans,
pubmed-meshheading:8708717-Infusions, Intravenous,
pubmed-meshheading:8708717-Leucovorin,
pubmed-meshheading:8708717-Male,
pubmed-meshheading:8708717-Middle Aged,
pubmed-meshheading:8708717-Neoplasm Metastasis,
pubmed-meshheading:8708717-Palliative Care,
pubmed-meshheading:8708717-Remission Induction,
pubmed-meshheading:8708717-Survival Rate
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
Weekly high-dose leucovorin versus low-dose leucovorin combined with fluorouracil in advanced colorectal cancer: results of a randomized multicenter trial. Study Group for Palliative Treatment of Metastatic Colorectal Cancer Study Protocol 1.
|
|
pubmed:affiliation |
II. Medizinische Klinik, Hämatologie-Onkologie, Krankenhaus Nordwest, Frankfurt, Germany.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study
|
