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pubmed-article:8698201pubmed:abstractTextWe have previously reported that alcoholics have increased titers of immunoglobulins reacting with protein adducts of hydroxyethyl free radicals. Because hydroxyethyl radicals are produced during ethanol metabolism by liver microsomes, the aim of this study was to determine whether such antibodies recognize microsomal proteins complexed with hydroxyethyl radicals.lld:pubmed
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pubmed-article:8698201pubmed:articleTitleCytochrome P4502E1 hydroxyethyl radical adducts as the major antigen in autoantibody formation among alcoholics.lld:pubmed
pubmed-article:8698201pubmed:affiliationDepartment of Medical Sciences, University of Torino, Novara, Italy.lld:pubmed
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