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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1996-8-30
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pubmed:abstractText |
We have previously reported that alcoholics have increased titers of immunoglobulins reacting with protein adducts of hydroxyethyl free radicals. Because hydroxyethyl radicals are produced during ethanol metabolism by liver microsomes, the aim of this study was to determine whether such antibodies recognize microsomal proteins complexed with hydroxyethyl radicals.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
111
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
206-16
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8698201-Adult,
pubmed-meshheading:8698201-Aged,
pubmed-meshheading:8698201-Autoantibodies,
pubmed-meshheading:8698201-Autoantigens,
pubmed-meshheading:8698201-Blotting, Western,
pubmed-meshheading:8698201-Cytochrome P-450 CYP2E1,
pubmed-meshheading:8698201-Cytochrome P-450 Enzyme System,
pubmed-meshheading:8698201-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8698201-Epitopes,
pubmed-meshheading:8698201-Female,
pubmed-meshheading:8698201-Humans,
pubmed-meshheading:8698201-Hydroxyl Radical,
pubmed-meshheading:8698201-Immunoglobulin A,
pubmed-meshheading:8698201-Immunoglobulin G,
pubmed-meshheading:8698201-Liver Cirrhosis, Alcoholic,
pubmed-meshheading:8698201-Male,
pubmed-meshheading:8698201-Microsomes, Liver,
pubmed-meshheading:8698201-Middle Aged,
pubmed-meshheading:8698201-Oxidoreductases, N-Demethylating
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pubmed:year |
1996
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pubmed:articleTitle |
Cytochrome P4502E1 hydroxyethyl radical adducts as the major antigen in autoantibody formation among alcoholics.
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pubmed:affiliation |
Department of Medical Sciences, University of Torino, Novara, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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