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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1996-8-30
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pubmed:abstractText |
Genomic variants of the hepatitis B virus (HBV) with core gene deletions have been identified in patients with chronic active hepatitis B, but the significance of these mutations in the course of chronic HBV infection remains unknown. The aim of this study was to longitudinally analyze the changes of HBV core gene deletion variants under the enhanced immune pressure of interferon alfa treatment and hepatitis B e antigen (HBeAg) to antibody to hepatitis B e antigen (anti-HBe) seroconversion.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0016-5085
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
111
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
183-92
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8698197-Adult,
pubmed-meshheading:8698197-Aged,
pubmed-meshheading:8698197-Base Sequence,
pubmed-meshheading:8698197-Chronic Disease,
pubmed-meshheading:8698197-Female,
pubmed-meshheading:8698197-Gene Deletion,
pubmed-meshheading:8698197-Genes, Viral,
pubmed-meshheading:8698197-Hepatitis B,
pubmed-meshheading:8698197-Hepatitis B Antibodies,
pubmed-meshheading:8698197-Hepatitis B e Antigens,
pubmed-meshheading:8698197-Hepatitis B virus,
pubmed-meshheading:8698197-Humans,
pubmed-meshheading:8698197-Interferon-alpha,
pubmed-meshheading:8698197-Longitudinal Studies,
pubmed-meshheading:8698197-Male,
pubmed-meshheading:8698197-Middle Aged,
pubmed-meshheading:8698197-Molecular Sequence Data,
pubmed-meshheading:8698197-Mutation,
pubmed-meshheading:8698197-Recombinant Proteins,
pubmed-meshheading:8698197-Viral Core Proteins
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pubmed:year |
1996
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pubmed:articleTitle |
Hepatitis B virus variants with core gene deletions in the evolution of chronic hepatitis B infection.
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pubmed:affiliation |
Institute of Liver Studies, King's College School of Medicine and Dentistry, London, England.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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