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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
12
|
| pubmed:dateCreated |
1996-8-26
|
| pubmed:abstractText |
Seven new sesquiterpenes, majapolenes A [1] and B [2], majapolone [3], and majapols A [4], B [5], C [6], and D [7], were isolated from a Philippine collection of Laurencia majuscula. With the exception of majapolene B [2], all compounds were isolated as inseparable diastereomeric mixtures. Structure elucidation was achieved by spectroscopic methods. Majapolene A [1], a dioxabicyclo[2.2.2]-alkene, displayed modest activity in the NCI 60-cell line cytotoxicity screen. Majapolene A was also found as a major component of a Philippine collection of Laurencia caraibica.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0163-3864
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
58
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1848-60
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:8691206-Antineoplastic Agents,
pubmed-meshheading:8691206-Bridged Compounds,
pubmed-meshheading:8691206-Drug Screening Assays, Antitumor,
pubmed-meshheading:8691206-Humans,
pubmed-meshheading:8691206-Magnetic Resonance Spectroscopy,
pubmed-meshheading:8691206-Philippines,
pubmed-meshheading:8691206-Rhodophyta,
pubmed-meshheading:8691206-Sesquiterpenes,
pubmed-meshheading:8691206-Tumor Cells, Cultured
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Majapolene A, a cytotoxic peroxide, and related sesquiterpenes from the red alga Laurencia majuscula.
|
| pubmed:affiliation |
Division of Cancer Treatment, National Cancer Institute, Frederick, Maryland 21702-1201, USA.
|
| pubmed:publicationType |
Journal Article
|