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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1996-8-29
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pubmed:abstractText |
The cAMP-dependent Cl- conductance in heart is believed to be due to cardiac expression of the cystic fibrosis transmembrane conductance regulator (CFTR). While CFTR expressed in rabbit and guinea-pig heart (CFTRcardiac) is an alternatively spliced isoform of the epithelial gene product, little information is known regarding possible expression of CFTR in primate heart. In this study, we examined molecular expression of CFTR in human and simian atrium and ventricle and functional expression of cAMP-dependent Cl- currents in isolated human atrial and simian ventricular cells.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
615-24
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8689654-Aged,
pubmed-meshheading:8689654-Animals,
pubmed-meshheading:8689654-Base Sequence,
pubmed-meshheading:8689654-Chloride Channels,
pubmed-meshheading:8689654-Cystic Fibrosis,
pubmed-meshheading:8689654-Cystic Fibrosis Transmembrane Conductance Regulator,
pubmed-meshheading:8689654-DNA Primers,
pubmed-meshheading:8689654-Female,
pubmed-meshheading:8689654-Gene Expression,
pubmed-meshheading:8689654-Heart Atria,
pubmed-meshheading:8689654-Heart Ventricles,
pubmed-meshheading:8689654-Humans,
pubmed-meshheading:8689654-Macaca fascicularis,
pubmed-meshheading:8689654-Male,
pubmed-meshheading:8689654-Middle Aged,
pubmed-meshheading:8689654-Molecular Sequence Data,
pubmed-meshheading:8689654-Myocardium,
pubmed-meshheading:8689654-Patch-Clamp Techniques,
pubmed-meshheading:8689654-Polymerase Chain Reaction
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pubmed:year |
1996
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pubmed:articleTitle |
CFTR chloride channels in human and simian heart.
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pubmed:affiliation |
Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno 89557-0046, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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