Linked Life Data

8689574

Source:http://linkedlifedata.com/resource/pubmed/id/8689574

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1996-8-23
pubmed:abstractText
The nucleolus is the site within the eukaryotic nucleus of transcription of rDNA, of processing of the rDNA transcripts, and of the formation of pre-ribosomal particles. We review current ideas for the molecular organization of these processes. The earliest transcriptional events take place near the junction of the fibrillar centers and the dense fibrillar component; nascent transcripts occupy the dense fibrillar component, and the later stages of pre-ribosome formation take place in the granular component. We review current knowledge of non-ribosomal nucleolar proteins. Nucleoli contain a group of proteins that bind RNA and are likely to act as chaperones to facilitate the molecular structural events in the folding and interaction of the many components of ribosomes. Some of these nucleolar proteins are also engaged in a shuttling cycle between the nucleus and the cytoplasm and may serve to transport other proteins.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1081-0706
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
93-121
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
The nucleolus.
pubmed:affiliation
Department of Cell Biology, John Innes Centre, Colney, Norwich, UK.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't