Linked Life Data

8689557

Source:http://linkedlifedata.com/resource/pubmed/id/8689557

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1996-8-23
pubmed:abstractText
Listeria monocytogenes and Shigella flexneri are unrelated bacterial pathogens that have independently evolved similar strategies of survival within an infected host animal. Bacteria coming into contact with the surface of an epithelial cell induce cytoskeletal rearrangements resulting in phagocytosis. They then secrete enzymes that degrade the phagosomal membrane, releasing the bacteria into the host cytoplasm. Intracytoplasmic bacteria move rapidly, in association with a "comet tail" made up of host cell actin filaments. When moving bacteria reach the cell margin, they push out long protrusions with the bacteria at the tips that are then taken up by neighboring cells, allowing the infection to spread from cell to cell. This review summarizes what is currently known about the interactions between the bacteria and the host at each stage of the infection and discusses what mammalian cell biologists can learn by studying bacterial pathogens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1081-0706
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-39
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
The cell biology of infection by intracellular bacterial pathogens.
pubmed:affiliation
Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't