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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1996-8-29
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pubmed:abstractText |
Conditioned place preference (CPP) paradigm has been used to test ethanol (EtOH) rewarding properties after repeated (20 days) injections of EtOH. Rats injected with 0.5 g/kg ip of EtOH during pre-exposure period and CPP procedure showed significant place preference to the compartment paired with the drug. Animals receiving higher dose of EtOH (1.0 g/kg) showed no CPP but rather relative aversion to the paired compartment (relatively to saline-treated group). Our result suggests a development of sensitization to EtOH rewarding effect after prolonged administration of low dose of EtOH.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1230-6002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
189-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8688894-Animals,
pubmed-meshheading:8688894-Conditioning (Psychology),
pubmed-meshheading:8688894-Ethanol,
pubmed-meshheading:8688894-Male,
pubmed-meshheading:8688894-Random Allocation,
pubmed-meshheading:8688894-Rats,
pubmed-meshheading:8688894-Rats, Wistar,
pubmed-meshheading:8688894-Reward
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pubmed:articleTitle |
Conditioned place preference after prolonged pre-exposure to ethanol.
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pubmed:affiliation |
Department of Pharmacology and Physiology of the Nervous System, Institute of Psychiatry and Neurology, Warszawa, Poland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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