Linked Life Data

8687123

Source:http://linkedlifedata.com/resource/pubmed/id/8687123

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-8-21
pubmed:abstractText
Development of new approaches to ameliorate tumor hypoxia may require understanding of the relative importance of supply vs. demand. On the demand side, abnormalities in energy metabolism are known to be related to defects in regulation of respiratory enzymes, combined with high demand for energy caused by cell proliferation. On the supply side deficiencies in efficiency of nutrient supply, such as low vascular density and uneven vascular distribution appear to play important roles. In theoretical simulations based on actual in vivo data, however, modulation of oxygen consumption is much more efficient in affecting oxygen transport than modification of delivery.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0250-7005
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
741-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Tumor oxygenation: a matter of supply and demand.
pubmed:affiliation
Department of Radiation Oncology, Duke University, Durham, NC 27710, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review