| pubmed-article:8686760 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8686760 | lifeskim:mentions | umls-concept:C2350570 | lld:lifeskim |
| pubmed-article:8686760 | lifeskim:mentions | umls-concept:C0917798 | lld:lifeskim |
| pubmed-article:8686760 | lifeskim:mentions | umls-concept:C1138427 | lld:lifeskim |
| pubmed-article:8686760 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
| pubmed-article:8686760 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8686760 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:8686760 | lifeskim:mentions | umls-concept:C0205234 | lld:lifeskim |
| pubmed-article:8686760 | lifeskim:mentions | umls-concept:C1707391 | lld:lifeskim |
| pubmed-article:8686760 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8686760 | pubmed:dateCreated | 1996-8-21 | lld:pubmed |
| pubmed-article:8686760 | pubmed:abstractText | The endothelial and smooth muscle integrin alphaVbeta3, a receptor for vitronectin and fibrinogen, participates in angiogenesis associated with wound healing and tumorigenicity. The microvascular expression of alphavbeta3 and fibrin during experimental middle cerebral artery occlusion and reperfusion in a nonhuman primate model was examined by computer-assisted video imaging microscopy. No microvascular expression of alphavbeta3 was seen in the control subjects (n = 3) or the non-ischemic basal ganglia of subjects undergoing 2-hour MCA:O (middle cerebral artery occlusion) or 3-hour occlusion with 1-hour (n = 3), 4-hour (n = 3), and 24-hour (n = 3) reperfusion. In the ischemic territory, alphavbeta3 appeared initially at 2 hours of middle cerebral artery occlusion. Up-regulation of alphavbeta3 was confined to the media of 30.0- to 50.0-micron-diameter arterioles in the ischemic core and correlated significantly with fibrin deposition in those vessels (P < 0.0005). Integrin alphavbeta3 and its ligand fibrinogen appear in a subpopulation of microvessels after focal cerebral ischemia. | lld:pubmed |
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| pubmed-article:8686760 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8686760 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8686760 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8686760 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8686760 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:8686760 | pubmed:issn | 0002-9440 | lld:pubmed |
| pubmed-article:8686760 | pubmed:author | pubmed-author:OkadaYY | lld:pubmed |
| pubmed-article:8686760 | pubmed:author | pubmed-author:KoziolJ AJA | lld:pubmed |
| pubmed-article:8686760 | pubmed:author | pubmed-author:ChereshD ADA | lld:pubmed |
| pubmed-article:8686760 | pubmed:author | pubmed-author:CopelandB RBR | lld:pubmed |
| pubmed-article:8686760 | pubmed:author | pubmed-author:del ZoppoG... | lld:pubmed |
| pubmed-article:8686760 | pubmed:author | pubmed-author:HamannG FGF | lld:pubmed |
| pubmed-article:8686760 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8686760 | pubmed:volume | 149 | lld:pubmed |
| pubmed-article:8686760 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8686760 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8686760 | pubmed:pagination | 37-44 | lld:pubmed |
| pubmed-article:8686760 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:8686760 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8686760 | pubmed:articleTitle | Integrin alphavbeta3 is expressed in selected microvessels after focal cerebral ischemia. | lld:pubmed |
| pubmed-article:8686760 | pubmed:affiliation | Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, USA. | lld:pubmed |
| pubmed-article:8686760 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8686760 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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