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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1977-7-29
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pubmed:abstractText |
Of 488 006 neonates tested by Guthrie screening 58 showed values above 2.5 mg/100 ml. Thirty-two showed values between 2.5 mg/100 ml and 15 mg/100 ml. Eighteen of these infants appeared to have phenylketonuria (PKU) and fourteen to have persistent hyperphenylalaninemia (HPA). Neither the initial Guthrie test-value nor the confirmatory test were able to differentiate between these two conditions. Consequently a phenylalanine restricted diet is started in any child with serumphenylalanine values exceeding 10 mh/100 ml (605 micronmol/l). The data show that the course of the dietary tolerance of phenylalanine and a 24-hour phenylalanine load test will differentiate infants with PKU from those with HPA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0001-656X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
339-44
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:868515-Denmark,
pubmed-meshheading:868515-Female,
pubmed-meshheading:868515-Humans,
pubmed-meshheading:868515-Infant, Newborn,
pubmed-meshheading:868515-Infant, Newborn, Diseases,
pubmed-meshheading:868515-Male,
pubmed-meshheading:868515-Mass Screening,
pubmed-meshheading:868515-Phenylalanine,
pubmed-meshheading:868515-Phenylketonurias,
pubmed-meshheading:868515-Tyrosine
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pubmed:year |
1977
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pubmed:articleTitle |
On indications for treatment of the hyperphenylalaninemic neonate.
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pubmed:publicationType |
Journal Article
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