pubmed-article:8683575 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8683575 | lifeskim:mentions | umls-concept:C0318255 | lld:lifeskim |
pubmed-article:8683575 | lifeskim:mentions | umls-concept:C0231239 | lld:lifeskim |
pubmed-article:8683575 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
pubmed-article:8683575 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:8683575 | lifeskim:mentions | umls-concept:C0440043 | lld:lifeskim |
pubmed-article:8683575 | lifeskim:mentions | umls-concept:C1705994 | lld:lifeskim |
pubmed-article:8683575 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
pubmed-article:8683575 | lifeskim:mentions | umls-concept:C1513492 | lld:lifeskim |
pubmed-article:8683575 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:8683575 | pubmed:dateCreated | 1996-8-20 | lld:pubmed |
pubmed-article:8683575 | pubmed:abstractText | Rotation of the Na(+)-driven flagellar motor of Vibrio alginolyticus was investigated under the influence of inhibitors specific to the motor, amiloride and phenamil. The rotation rate of a single flagellum on a cell stuck to a glass slide was examined using laser dark-field microscopy. In the presence of 50 mM NaCl, the average rotation rate (omega) was about 600 r.p.s. with a standard deviation (sigma omega) of 9% of omega. When omega was decreased to about 200 r.p.s. by the presence of 1.5 mM amiloride, sigma omega increased to 15% of omega. On the other hand, when omega was decreased to about 200 r.p.s. by the addition of 0.6 microM phenamil, a large increase in sigma omega up to 50% of omega, was observed. Similarly large fluctuations were observed at other concentrations of phenamil. These observations suggest that dissociation of phenamil from the motor was much slower than that of amiloride. A very low concentration of phenamil caused a transient but substantial reduction in rotation rate. This might suggest that binding of only a single molecule of phenamil strongly inhibits the torque generation in the flagellar motor. | lld:pubmed |
pubmed-article:8683575 | pubmed:language | eng | lld:pubmed |
pubmed-article:8683575 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8683575 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8683575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8683575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8683575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8683575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8683575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8683575 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8683575 | pubmed:month | Jun | lld:pubmed |
pubmed-article:8683575 | pubmed:issn | 0022-2836 | lld:pubmed |
pubmed-article:8683575 | pubmed:author | pubmed-author:KudoSS | lld:pubmed |
pubmed-article:8683575 | pubmed:author | pubmed-author:LYLER ERE | lld:pubmed |
pubmed-article:8683575 | pubmed:author | pubmed-author:HommaMM | lld:pubmed |
pubmed-article:8683575 | pubmed:author | pubmed-author:SugiyamaSS | lld:pubmed |
pubmed-article:8683575 | pubmed:author | pubmed-author:MuramotoKK | lld:pubmed |
pubmed-article:8683575 | pubmed:author | pubmed-author:KawagishiII | lld:pubmed |
pubmed-article:8683575 | pubmed:author | pubmed-author:MagariyamaYY | lld:pubmed |
pubmed-article:8683575 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8683575 | pubmed:day | 21 | lld:pubmed |
pubmed-article:8683575 | pubmed:volume | 259 | lld:pubmed |
pubmed-article:8683575 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8683575 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8683575 | pubmed:pagination | 687-95 | lld:pubmed |
pubmed-article:8683575 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:8683575 | pubmed:year | 1996 | lld:pubmed |
pubmed-article:8683575 | pubmed:articleTitle | Rotational fluctuation of the sodium-driven flagellar motor of Vibrio alginolyticus induced by binding of inhibitors. | lld:pubmed |
pubmed-article:8683575 | pubmed:affiliation | Department of Molecular Biology, Faculty of Science, Nagoya University, Japan. | lld:pubmed |
pubmed-article:8683575 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8683575 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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