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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
7
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pubmed:dateCreated |
1996-8-22
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pubmed:abstractText |
The CD20 B-lymphocyte surface antigen expressed by B-cell lymphomas is an attractive target for radioimmunotherapy, treatment using radiolabeled antibodies. We conducted a phase I dose-escalation trial to assess the toxicity, tumor targeting, and efficacy of nonmyeloablative doses of an anti-CD20 monoclonal antibody (anti-B1) labeled with iodine-131 (131I) in 34 patients with B-cell lymphoma who had failed chemotherapy.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
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pubmed:month |
Jul
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|
pubmed:issn |
0732-183X
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pubmed:author |
pubmed-author:EstesJJ,
pubmed-author:FennerM CMC,
pubmed-author:FisherSS,
pubmed-author:FrancisI RIR,
pubmed-author:GlennS DSD,
pubmed-author:KaminskiM SMS,
pubmed-author:MilikA WAW,
pubmed-author:ReganDD,
pubmed-author:RossC WCW,
pubmed-author:TuckMM,
pubmed-author:VIGLHH,
pubmed-author:ZasadnyK RKR
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1974-81
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8683227-Adult,
pubmed-meshheading:8683227-Aged,
pubmed-meshheading:8683227-Antibodies, Monoclonal,
pubmed-meshheading:8683227-Antigens, CD20,
pubmed-meshheading:8683227-Dose-Response Relationship, Radiation,
pubmed-meshheading:8683227-Female,
pubmed-meshheading:8683227-Humans,
pubmed-meshheading:8683227-Iodine Radioisotopes,
pubmed-meshheading:8683227-Lymphoma, B-Cell,
pubmed-meshheading:8683227-Male,
pubmed-meshheading:8683227-Middle Aged,
pubmed-meshheading:8683227-Radioimmunotherapy,
pubmed-meshheading:8683227-Remission Induction
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pubmed:year |
1996
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|
pubmed:articleTitle |
Iodine-131-anti-B1 radioimmunotherapy for B-cell lymphoma.
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pubmed:affiliation |
Department of Internal Medicine, University of Michigan, Ann Arbor 48109-0724, USA. mkaminsk@umich.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Clinical Trial, Phase I
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