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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1996-8-16
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pubmed:abstractText |
Cytotoxic T lymphocytes (CTLs) may play a role in host defence against hepatitis C virus (HCV) infection, and HCV-specific CTL epitopes may be included in vaccines to induce protective CTLs. We identified three new epitopes within the HCV nucleoprotein recognized by CTLs. HCV nucleoprotein residues 28-37 are the minimal epitope recognized by CTLs in association with the class I human leukocyte antigen B60, and epitopes in HCV nucleoprotein residues 111-130 and 161-180 are both recognized by CTLs in association with the class II human leukocyte antigen DRBI*08032.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-1317
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
77 ( Pt 6)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1305-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8683220-Amino Acid Sequence,
pubmed-meshheading:8683220-Antibody Specificity,
pubmed-meshheading:8683220-Epitopes,
pubmed-meshheading:8683220-Genotype,
pubmed-meshheading:8683220-Hepacivirus,
pubmed-meshheading:8683220-Hepatitis C,
pubmed-meshheading:8683220-Hepatitis C Antibodies,
pubmed-meshheading:8683220-Humans,
pubmed-meshheading:8683220-Molecular Sequence Data,
pubmed-meshheading:8683220-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:8683220-Viral Core Proteins
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pubmed:year |
1996
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pubmed:articleTitle |
Three new cytotoxic T cell epitopes identified within the hepatitis C virus nucleoprotein.
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pubmed:affiliation |
Hepatology Division, Jichi Medical School, Tochigi, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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