Linked Life Data

868207

Source:http://linkedlifedata.com/resource/pubmed/id/868207

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-7-23
pubmed:abstractText
C57BL/10 inbred mice produce a "natural" antibody which in the presence of complement selectively lyses human blood group A erythrocytes, and the sera of females display significantly higher levels than the sera of males. This pronounced anti-A hemolysin production in females follows the appearance of specific endogenous A-determinants which are associated with water-soluble ovarian glycolipids specifically blocking the syngeneic anti-A hemolysin activity. Moreover, this hemolysin activity develops poorly in mice ovariectomized at the age of 20 days. The coincidental production of (auto)antigenic structures in morphologically and functionally normal ovarian tissue and of antibodies against them is thought to be tolerated through the modulation of a thymusdirected control mechanism.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0340-904X
pubmed:author
pubmed:issnType
Print
pubmed:volume
153
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
74-84
pubmed:dateRevised
2008-2-12
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Age-dependent appearance of A-specific ovarian glycolipids and syngeneic "natural" anti-A hemolysin in mice.
pubmed:publicationType
Journal Article