rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1996-8-16
|
pubmed:abstractText |
A case of adrenal tumor producing 11-deoxycorticosterone, 18-hydroxy-11-deoxycorticosterone and aldosterone is reported. A 55-year-old woman had hypertension, hypokalemia, low plasma renin activity and an adrenal tumor. The plasma level of aldosterone was normal, and the levels of 11-deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone were extremely high. After the tumor removal, the plasma level of aldosterone decreased and plasma levels of 11-deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone were normalized. The tumor was benign adenoma and the production of steroid hormones was under control of adrenocorticotropic hormone. The enzyme activity of 21-hydroxylation in the tumor was elevated and that of 11 beta-hydroxylation was decreased compared with the adjacent tissue.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0918-2918
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
35
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
123-8
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:8680100-18-Hydroxydesoxycorticosterone,
pubmed-meshheading:8680100-Adenoma,
pubmed-meshheading:8680100-Adrenal Gland Neoplasms,
pubmed-meshheading:8680100-Aldosterone,
pubmed-meshheading:8680100-Desoxycorticosterone,
pubmed-meshheading:8680100-Female,
pubmed-meshheading:8680100-Humans,
pubmed-meshheading:8680100-Hydrocortisone,
pubmed-meshheading:8680100-Hypertension,
pubmed-meshheading:8680100-Hypokalemia,
pubmed-meshheading:8680100-Middle Aged,
pubmed-meshheading:8680100-Renin,
pubmed-meshheading:8680100-Tomography, X-Ray Computed
|
pubmed:year |
1996
|
pubmed:articleTitle |
Adrenal tumor producing 11-deoxycorticosterone, 18-hydroxy-11-deoxycorticosterone and aldosterone.
|
pubmed:affiliation |
Department of Internal Medicine, Arida Municipal Hospital, Wakayama.
|
pubmed:publicationType |
Journal Article,
Case Reports
|