Linked Life Data

8680074

Source:http://linkedlifedata.com/resource/pubmed/id/8680074

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1996-8-22
pubmed:abstractText
A major objective for pharmacokineticians is to help practicians to define drug administration protocols. Protocols are generally designed for all the patients but inter individual variability would need monitoring for each patient. Computers are widely used to determine pharmacokinetic parameters and to try to individualize drug administration. Severals examples are summarily described: terminal half-life determination by regression; model fitting to experimental data; Bayesian statistics for individual dose adaptation; population pharmacokinetic methods for parameter evaluation. These methods do not replace the pharmacokinetician thought but could make possible drug administration taking into account individual characteristics.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0007-4551
pubmed:author
pubmed:issnType
Print
pubmed:volume
82 Suppl 5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
607s-611s
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[Contribution of computers to pharmacokinetics, Bayesian approach and population pharmacokinetics].
pubmed:affiliation
Laboratoire de pharmacodynamie clinique, centre Oscar-Lambret, Lille, France.
pubmed:publicationType
Journal Article, English Abstract