|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1996-8-20
|
|
pubmed:abstractText |
Allergen-specific T cells from atopic patients generally belong to the T-helper type 2 subset. IL-4 and IL-13 produced by these cells induce IgE synthesis by B cells and play a major role in allergic disease mediated by IgE. Recent advances in our understanding of the differentiation and IgE-inducing activities of T-helper type 2 cells suggest that targeting allergen-specific T cells may provide a novel way to intervene in allergy.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0952-7915
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
7
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
771-8
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:8679118-Animals,
pubmed-meshheading:8679118-Cell Differentiation,
pubmed-meshheading:8679118-Humans,
pubmed-meshheading:8679118-Immunoglobulin E,
pubmed-meshheading:8679118-Interferon-gamma,
pubmed-meshheading:8679118-Interleukin-13,
pubmed-meshheading:8679118-Interleukin-4,
pubmed-meshheading:8679118-Lymphocyte Activation,
pubmed-meshheading:8679118-Mice,
pubmed-meshheading:8679118-Mice, SCID,
pubmed-meshheading:8679118-Models, Immunological,
pubmed-meshheading:8679118-Receptors, Interleukin,
pubmed-meshheading:8679118-Th2 Cells
|
|
pubmed:year |
1995
|
|
pubmed:articleTitle |
Antagonizing the differentiation and functions of human T helper type 2 cells.
|
|
pubmed:affiliation |
Human Immunology Department, Research Institute of Molecular and Cellular Biology, Palo Alto, CA 94304-1104, USA.
|
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|
